In details

Lipolysis and Lipogenesis

Glucose molecule


When we eat carbohydrates, they are turned into glucose, and it enters the bloodstream.

When the concentration of glucose deposited in the blood exceeds its maximum limit, its excess is removed by the liver, and the liver stores it inside as glycogen.

Given this, it is correct to say that ingesting glucose, consequently increase the concentration of glycogen within the liver.

In turn, when in excess, glycogen is broken down by the liver and its excess is eliminated in the blood and, consequently, the concentration of fatty acids in the bloodstream will be increased.

Excess fatty acids in the blood are removed by the skin and the skin will store it inside cells known as adipocytes (fat storage cells). This storage will take place in the form of fat.


Lipolysis is exactly the opposite process of lipogenesis. When the blood is below normal glucose concentration, it receives glucose from the liver resulting from the breakdown of glycogen.

The liver, in turn, to keep its glycogen level stable, removes fatty acids from the blood, turning them into glycogen.

When the blood, which has been removed by the liver from fatty acids, reaches the skin, it breaks down the fat stored in its adipocytes and introduces it into the blood as fatty acids.

Factors that influence lipolysis and lipogenesis are: caloric intake, energy expenditure, hormonal, psychological, socio-familial and hereditary.


People with hypoglycemia cannot do lipolysis because it is a disorder that inhibits it.